Preheat the oven to 375°F (190°C). Heat avocado oil in a skillet over medium heat. Add ground turkey, breaking it up as it cooks. Add a pinch of salt. Once browned, stir in onion powder, garlic powder, and oregano.
Pour in the tomato basil sauce, stir, and let it simmer for 4-5 minutes. Turn off the heat. Mix the blended cottage cheese, crumbled goat cheese, grated Parmesan and spinach. Stir until combined and taste. Adjust seasoning if necessary.
Spread a thin layer of the sauce at the bottom of a greased 9x13-inch baking dish. Layer lasagna noodles over the sauce, followed by more of the sauce on top along with a sprinkle of shredded mozz or goat cheese (if using.)
Repeat the layers with the remaining sauce, noodles and cheese. Sprinkle more shredded cheese on top, if using. Cover with foil and bake for 35 minutes. Remove foil and bake for another 10 minutes. Let it rest for 5 minutes before serving.